Victor Osimhen, Paul Onuachu, Kelechi Iheanacho will lead about a dozen Nigeria stars in action tonight in the UEFA Europa League.
Nigerian interest in the second-tier Europa League will be concentrated on the clash between Leicester City, who have Iheanacho, Wilfred Ndidi and Ademola Lookman, and Napoli, whose attack will be spearheaded by Osimhen.
Osimhen was initially a huge doubt for this fixture due to Coronavirus travel restrictions and injury.
Onuachu and Ike Ugbo, who has applied to FIFA to play for the Super Eagles, are the strikers Genk hope will shoot down Austrian club Rapid Vienna.
Scottish champions Rangers could line up Leon Balogun, Joe Aribo and Calvin Bassey against top French club Lyon, while Bright Osayi-Samuel will hope to continue his goal-scoring form for Fenerbahce at German Bundesliga outfit Eintracht Frankfurt.
Henry Onyekuru has already scored for Greek champions Olympiacos in the qualifying rounds of the competition.
He will hope to continue with such form when Belgian club Antwerp, who though will be without the injured Alhassan Yusuf.
Danish club FC Midtjylland have for many years showcased Nigerian talent and will hope to continue so by parading youngster Raphael Onyedika in the home tie against Bulgarian club Ludogorets.
The promising Onyedika, 20, has come through to the first team after a loan stint in the lower league in Denmark last season.