The friendly between Nigeria, who will be represented by players from the NPFL, and Mexico will kick off by 4am Sunday, which will be 8pm on Saturday in Los Angeles, USA.
The game will be played at the 77,500-capacity Los Angeles Memorial Coliseum, which officials said is expected to be sold out.
The Nigerian team have already landed in US.
They include Enyimba winger Anayo Iwuala, who has already won four caps for the Super Eagles, as well as goalkeeper John Noble, who has been called up to recent games by coach Gernot Rohr.
Heartland goalkeeper Ikechukwu Ezenwa has been ruled out of the game on account of an ankle injury.
He is now to be replaced by Tottenham U23 goalkeeper Joshua Oluwayemi.
This will be the sixth meeting between Nigeria and Mexico with four of these games ending in draws.