Mukhtar Sanusi, Yunusa Muritala, Olarenwaju Kayode and Leke James were among several Nigeria stars, who featured in the newly founded UEFA Conference League today.
Sanusi, 19, started for Dynamo Brest of Belarus and was replaced in the 63rd minute.
His team fell 2-1 at Czech club Vitoria Plzen with the return leg in Belarus next Thursday.
Kayode started for Turkish club Sivasspor in a 1-0 win at Petrocub of Moldova.
He was replaced by compatriot Leke James in the 80th minute.
Yunusa Muritala was a second half sub for Latvian club Riga in a 2-0 home win over Shkendija from Northern Macedonia.
Akinkunmi Amoo also played for Swedish club Hammarby in a 3-1 home win over Maribor.
He started the game before he was replaced in the 82nd minute.
