Emmanuel Dennis justified his start for Club Brugge by providing the assist for the Belgian champions to open scoring at rivals KRC Genk, while Super Eagles call-up Cyriel Dessers missed a penalty for the home team.
It was Club Brugge first win of the new season after they lost two and drew one of their first three games.
Dennis, who has long been linked with a transfer away from Club Brugge, crossed the ball for it to be headed home after 19 minutes.
Genk then had a chance to draw level from the penalty spot at the start of the second half, but Dessers, who started the game after compatriot Paul Onuachu was withdrawn from the starting XI because he is not 100% fit, saw his shot come off the post.
Both David Okereke and Dennis also had chances to score for Club Brugge, before the champions finally snatched a late winner after the home team restored parity from the penalty spot courtesy of VAR.
