Super Eagles have called up Napoli striker Victor Osimhen for AFCON qualifiers versus Benin and Lesotho, while uncapped Sadiq Umar from Spanish club UD Almeria and Enyimba goalkeeper John Noble have been included on a 24-man squad.
Osimhen has had to endure a shoulder injury on international duty that sidelined him for more than three months, Coronavirus as well as a number of controversies since his record transfer to Italy from French club Lille.
He has netted four goals in the qualifiers thus far.
Sadiq Umar has been on blistering form for Almeria in the Spanish second division having scored 14 goals as his club look set to return to the top league.
Noble was the hero when Enyimba edged past fellow Nigerian club Rivers United on penalties to qualify to the group stage of the CAF Confederation Cup.
He is the only player based in the domestic league on the main squad and he has been listed alongside Sparta Rotterdam goalkeeper Maduka Okoye and Francis Uzoho, who was the country’s No 1 at the 2018 World Cup in Russia.
Captain Ahmed Musa was a surprise inclusion as he has been without a club since October and coach Gernot Rohr has often maintained he will not consider players who are not active at their clubs.
Nigeria visit Benin on March 27 before they host Lesotho on Lagos three days to conclude the qualifying series for the 2021 Africa Cup of Nations, which will be staged next year in Cameroon.
The Eagles lead their qualifying group with eight points, closely followed by Benin, who have seven points.
Sierra Leone have three points with only the top two teams advancing to the tournament proper.
The full squad
Goalkeepers: Maduka Okoye (Sparta Rotterdam/NED), Francis Uzoho (Apoel Nicosia/CYP), John Noble (Enyimba)
Defenders: William Ekong (Watford/ENG), Kenneth Omeruo (CD Leganes/SPA), Leon Balogun (Rangers/SCO),Chidozie Awaziem (Boavista/POR), Jamilu Collins (Paderborn/GER), Zaidu Sanusi (FC Porto/POR), Ola Aina (Fulham/ENG), Tyronne Ebuehi (FC Twente/NED)
Midfielders:Wilfred Ndidi (Leicester City/ENG), Oghenekaro Etebo (Galatasaray/TUR), Semi Ajayi (West Bromwich Albion/ENG), Shehu Abdullahi (Omonia Nicosia/CYP), Joe Aribo (Rangers/SCO)
Forwards: Ahmed Musa (no club), Moses Simon (FC Nantes/FRA), Alex Iwobi (Everton/ENG), Samuel Kalu (Bordeaux/FRA), Victor Osimhen (Napoli /ITA), Kelechi Iheanacho (Leicester City/ENG), Samuel Chukwueze (Villarreal CF/SPA), Sadiq Umar (UD Almeria/SPA)
Standby: Daniel Akpeyi (Kaizer Chiefs/RSA), Paul Onuachu (Genk/BEL), Terem Moffi (FC Lorient), Henry Onyekuru (Galatasaray/TUR), Michael Olise (Reading/ENG), Peter Olayinka (Slavia Prague/Czech), Adekunle Adeleke (Abia Warriors)